Table of Contents

Genomics and Proteomics.- Rethinking Sepsis: New Insights from Gene Expression Profiling Studies.- Mitochondrial Genetics and Sepsis.- Lung Proteomics in Intensive Care.- Inflammatory Response.- The Host Response to Sepsis.- Endotoxin Tolerance:Mechanisms and Clinical Applicability.- Oxidative Stress and Endothelial Dysfunction during Sepsis.- Measurement of Carbon Monoxide: From Bench to Bedside.- Monitoring Immune Dysfunction in Septic Patients: Toward Tailored Immunotherapy.- Current and Future Management of Sepsis.- Source Control in the ICU.- IgM-enriched Immunoglobulins in Sepsis.- Clarithromycin: A Promising Immunomodulator in Sepsis.- High-flow Hemofiltration as an Adjunctive Therapy in Sepsis.- Economic and Social Burden of Severe Sepsis.- Proposed Targets for New Therapies.- Lymphocyte Apoptosis in Sepsis and Potential Anti-apoptotic Strategies.- The Pivotal Role of Beta-adrenoreceptors in Critical Illness Pathophysiology.- Non-septic Acute Lung Injury and Inflammation: Role of TLR4.- Hydrogen Sulfide: A Metabolic Modulator and a Protective Agent in Animal Models of Reperfusion Injury.- Septic Shock.- 'Myocardial Depression' or' Septic Cardiomyopathy'?.- Determinants of Tissue PCO2 in Shock and Sepsis: Relationship to the Microcirculation.- Refining the Tools for Early Goal-directed Therapy in Septic Shock.- Intravenous Fluids.- Hyperchloremic Metabolic Acidosis: More than Just a Simple Dilutional Effect.- Old versus New Starches: What do We Know about their Differences?.- Impact of Hydroxyethyl Starch on Renal Function.- Rational Approach to Fluid Therapy in Acute Diabetic Ketoacidosis.- Hemodynamic Support.- Cardiac Filling Volumes and Pressures in Assessing Preload Responsiveness during Fluid Challenges.- Update on Preload Indexes: More Volume than Pressure.- Monitoring Arterial Blood Pressure and Cardiac Output using Central or Peripheral Arterial Pressure Waveforms.- Intrathoracic Pressure Regulation for the Treatment of Hypotension.- Functional Hemodynamic Monitoring: A Personal Perspective.- Airway Management.- Endotracheal Intubation in the ICU.- Pediatric Advanced Airway Management Training for Non-anesthesia Residents.- Automatic Tube Compensation in the Weaning Process.- Mechanical Ventilation.- Extracorporeal Membrane Oxygenation for Cardiac and Pulmonary Indications: Improving Patient Safety.- Patient-ventilator Interaction during Noninvasive Ventilation.- Variable Mechanical Ventilation: Breaking the Monotony.- Life-threatening Asthma: Focus on Lung Protection.- Respiratory Monitoring.- Bedside Monitoring of Diaphragm Electrical Activity during Mechanical Ventilation.- Electrical Impedance Tomography.- Regional Ventilation Delay Index: Detection of Tidal Recruitment using Electrical Impedance Tomography.- Different Approaches to the Analysis of Volumetric Capnography.- Variation in Extravascular Lung Water in ALI/ARDS Patients using Open Lung Strategy.- Clinical Utility of Extravascular Lung Water Measurements.- Perioperative Management.- Rationalizing the Use of Surgical Critical Care: The Role of Cardiopulmonary Exercise Testing.- Advanced Minimally Invasive Hemodynamic Monitoring of the High-risk Major Surgery Patient.- Post-pneumonectomy Pulmonary Edema.- The Role of Phenylephrine in Perioperative Medicine.- Role of the Calcium Sensitizer, Levosimendan, in Perioperative Intensive Care Medicine.- Inhaled Nitric Oxide Therapy in Adult Cardiac Surgery.- Cardiac Function.- Use of Natriuretic Peptides in the Emergency Department and the ICU.- Abnormalities of the ST Segment.- Functional Mitral Regurgitation in the Critically III.- Cardiopulmonary Resuscitation.- Feedback to Improve the Quality of CPR.- The Post-cardiac Arrest Syndrome.- Use of a Standardized Treatment Protocol for Post-cardiac Resuscitation Care.- Therapeutic Hypothermia after Cardiac Arrest.- Renal Function.- Biomarkers of Acute Kidney Injury in Critical Illness.- The Role of Biomarkers in Cardiac Surgery-associated Acute Kidney Injury.- Neutrophil Gelatinase- associated Lipocalin: An Emerging Biomarker for Angina Renalis.- Hepatosplanchnic Function.- How does Intra-abdominal Pressure Affect the Daily Management of My Patients?.- ICG Clearance Monitoring in ICH Patients.- Acute-on-Chrenic Liver Failure in Cirrhosis: Defining and Managing Organ Dysfunction.- Nutrition.- The Curse of Overfeedinc and the Blight of Underfeeding.- Enterai Feeding during Circulatory Failure: Myths and Reality.- Enterai Nutrition with Anti-inflammatory Lipids in ALI/ARDS.- Glutamine Supplementation in ICU Patients.- Glucose Control.- Burn Causes Prolonged Insulin Resistance and Hyperglycemia.- Glucose Variability in Critically III Patients.- Adrenal Function.- Corticosteroid Biology in Critical Illness: Modulatory Mechanisms and Clinical Implications.- Corticosteroid Treatment of Patients in Septic Shock.- Coagulation.- New Anticoagulants: Anti-lla or Anti-Xa agents?.- Emergency Reversal of Anticoagulants.- Neurological Aspects.- The Role of Imaging in Acute Brain Injury.- Monitoring and Managing Raised Intracranial Pressure after Traumatic Brain Injury.- Sepsis-associated Encephalopathy.- Malignancies.- Acute Tumor Lysis Syndrome: Diagnosis and Management.- Life-threatening Neurological Complications in Patients with Malignancies.- Should We Admit Critically III Cancer Patients to the ICU?.- Drug Dosing.- Optimizing Drug Dosing in the ICU.- Relevant CYP450-mediated Drug Interactions in the ICU.- Sedation and Analgesia.- Sedation and Pain Management in the ICU.- The Role of Dexmedetomidine in Intensite Care.- Monitoring Delirium in the ICU.- ICU Management.- Intensite Care for the Elderly: Current and Future Concerns.- ICU Performance: Managing with Balanced Scorecards.- End-of-Life Issues.- Towards a Neuro-scientific Explanation of Near-death Experiences?.- Managing Conflict at the End-of-Life.- Strengths and Weaknesses of Substitute Decision Making in the ICU.