Table of Contents

Preface; Understanding Central Mechanisms of Pain and Pain Modulation; Ion Channel Blockers in Clinical Pain Management; Spinal N-methyl-D-asparate Receptor Mechanisms of Central Sensitisation and Pain Following Tissue Injury; NMDA Receptor Antagonists and Clinical Pain Management; Plasticity of Signalling Molecules and their Associations after Chronic Morphine: Altered but not Lost Opiod Receptor-Coupled Functionality; Opiod for Pain Management; Inflammatory Cytokines in Preclinical Studies; Anti-Inflammatory Medications in Pain Management; Chronic Pain and the Sympathetic Nervous System: Mechanisms and Potential Implications for Pain Therapies; Mechanisms of Tricyclic Antidepressants in Pain Medicine; Antidepressant Medication in Clinical Pain Management; Developing Pain Pathways and Analgesic Mechanisms: Towards Translational Studies; Paediatric Pain: In Translation; Selective Serotonin Agonists for the Acute Management of Migraine; Gender Differences in Clinical Pain Management; Clinical Management of Cancer Pain; Alternative Medicine in Pain Management: Preclinical Evidence and Clinical Application; Index.