Table of Contents

The discovery and development of atorvastatin, a potent novel hypolipidemic agent, B.D. Roth; discovery of CEP-1347/KT-7515, an inhibitor of the JNK/SAPK pathway for the treatment of neurodegenerative diseases, M.S. Saporito, R.L. Hudkins, A.C. Maroney; discovery of second generation quinazolinone non-nucleoside reverse transcriptase inhibitors of HIV-1, J.W. Corbett, J.D. Rodgers; molecular modeling of opioid receptor-ligand complexes, I. McFadyen, T. Metzger, G. Subramanian, G. Poda, E. Jorvig, D.M. Ferguson.