Table of Contents

1 Origins of Genetic Toxicology.- 2 Fundamentals of Genetic Toxicity.- 3 The Consequences of Genotoxic Effects in Humans and Other Mammals.- 4 Screening Chemicals for Genotoxic Properties.- 5 Genetic Risk Estimation.- 6 Applications of Genetic Toxicology to Human and Environmental Monitoring.- 7 The Genetic Toxicology Laboratory.- 8 Descriptions and Evaluation of Genetic Toxicology Assays.- 9 Applications from Biotechnology Research to Genetic Toxicology.- 10 Genetic Toxicology and Its Role in the Study of Congenital Malformations.- Appendixes.- Appendix A: S9 Homogenate and S9 Mix.- Background.- S9 Batch Variability.- S9 Standardization.- S9 Stability.- S9 Storage.- Other S9 Problems.- References.- References.- Appendix C: Selection References and Reviews of Genetics and Genetic Toxicology.