Chapter 1 Introduction: The Tipping Point Part 2 I. Overview Chapter 3 1. The Good, the Bad, and the Ugly: A Story of Two Medications Chapter 4 2. An Ethical Framework Part 5 II. Specific Issues and Problems Chapter 6 3. The Pharmaceutical Industry and the Free Market Chapter 7 4. Patents, Generic Drugs, and Academic Science Chapter 8 5. Research and Profits Chapter 9 6. Suppression of Research Data Chapter 10 7. The Quality of Pharmaceutical Research Chapter 11 8. The Drug Rep: Historical Background Chapter 12 9. The Drug Rep Today Chapter 13 10. The Influence of Drug Reps: What the Data Show Chapter 14 11. Continuing Medical Education Chapter 15 12. Professional Organizations and Journal Advertising Chapter 16 13. The Industry and the Consumer Chapter 17 14. The FDA: From Patent Medicine to AIDS Drugs Chapter 18 15. The FDA and the Industry, 1990-2004 Part 19 III. Toward Solutions Chapter 20 16. Solutions: The Management and Divestment Strategies Chapter 21 17. Solutions Requiring Enhanced Professionalism in Medicine Chapter 22 18. Solutions Requiring Regulatory Reform Chapter 23 Epilogue: Industry Woes and Professional Opportunities
Howard Brody is professor and director for the Institute for the Medical Humanities, University of Texas Medical Branch at Galveston. Prior to this appointment, Dr. Brody was University Distinguished Professor of family practice, and philosophy at Michigan State University, where he also sat on the faculty of the Center for Ethics and Humanities in the Life Sciences; he served as director of the Center from 1985-2000. Dr. Brody completed his residency in family practice at the University of Virginia Medical Center. He received his MD from the College of Human Medicine, Michigan State University, in 1976, and his PhD in Philosophy, also from Michigan State University, in 1977. He currently sits on the board of the American Society for Bioethics and the Humanities, and specializes in ethics and the doctor-patient relationship. He has authored five books, among them Stories of Sickness (2002) and The Placebo Response: How You Can Release the Body's Inner Pharmacy for Better Health (2000). For up-to-date news about the issues covered in Hooked, visit Dr. Brody's new blog.
[Brody] aims for the measured cadences of the ethicist . . . calmly
laying out the relevant facts and then reasoning from basic
principles to determine whether the medicine-pharmaceutical
relationship, as it stands now, is an ethical one or not. That Dr.
Brody manages to deliver a hundred-odd pages of determinedly
objective analysis before he, too, lets the righteous indignation
roll should not really be called a failure of methodology: even as
he carefully lays out the facts in this impressively comprehensive
book, those facts begin to speak damningly for themselves . . . for
a detailed overview of this very jagged terrain, if not for a map
of the pathway out, a better general guide than this one is hard to
imagine.
*The New York Times*
Physicians, policy makers, and the public should thank Dr. Brody
for this major contribution to our understanding of the medical
profession and the corrupting influence on the profession of its
complex relationship with the pharmaceutical industry.
*Philip R. Lee, MD, Stanford University, and author of Pills,
Profits, and Politics*
The single best, most balanced, most comprehensive guide to the
current difficulties with the pharmaceutical industry that I have
ever read.
*Carl Elliott, University of Minnesota*
Dr. Howard Brody has written a powerful book that is relevant to
all out practices and questions the relationship between medicine
and the pharmaceutical industry.
*The Journal Of Nuclear Medicine, December 1, 2008*
In this extraordinary book, Dr. Howard Brody, a medical ethicist,
lays out in great detail what he judges to be Big Pharma's misdeeds
and the seduction of U.S. docs. His targets are the influence of
company drug reps, the suppression of negative research data, the
abuse of patents, phony advertising and weak oversight by the
FDA.
*Chicago Tribune*
Thoroughly documented, logically structured, and well written,
[Brody's] book offers a good starting point for discussing ethical
issues that impact us all. Recommended for all medical and public
libraries.
*Library Journal*
I highly acclaim and recommend this book to all physicians, medical
students, and those in policy-making positions regarding our broken
health-care system...It ought to be required reading for the
medical profession as a whole and a call to action to help us
regain the public's trust in our integrity, altruism, and
professional ethics.
*Explore: The Journal of Science and Healing*
It seems that no stone is left unturned in this 367-page book,
which can feel at times overwhelming but is without a doubt,
thorough.
*Health Affairs, September 2008*
This book is useful for any medical student or resident who, like
me, finds the practice of distributing free pens and lunches a nice
perk but an ineffective marketing strategy. Hooked is surely
worthwhile for the academic physician-investigator who struggles to
win grants, or for the rural practitioner.
*Anesthesia and Analgesia, September 2008*
The densely written book captures one's attention and reads like a
nonfiction thriller....I highly recommend this book to anyone who
wants to gain a thorough understanding of the relationship between
the pharmaceutical industry and the medical profession. This
knowledge provides a platform for the development of rational
solutions, which are sorely needed.
*JAMA: The Journal of the American Medical Association, (Jama)*
Hooked is a detailed analysis of the relationship between the
medical profession and the pharmaceutical industry primarily in the
United States. Hooked is well researched and well written. Brody's
style is fluent, helping make his arguments persuasive.
*Journal of Value Inquiry*
We still have too many doctors and patients who may be aware of
some of the deviances of the pharmaceutical industry, however,
consider these to be exceptional and of marginal importance. In
fact, if someone reads Brody's book, they will learn that fraud,
malpractice, and lying is an inbuilt phenomenon in the system of
clinical research, drug regulation, scientific publication, medical
training and drug advertisements. What Brody adds to our present
knowledge is a systematic collection of recommendations for
changing the present malfunctioning status quo. It is good to read
Brody's book, and it is good to have his reflections in our
minds.
*Metapsychology Online, July 7, 2009*
An extremely timely book, recommended.
*Pediatric Endocrinology Reviews, (Per)*
[Brody] aims for the measured cadences of the ethicist . . . calmly
laying out the relevant facts and then reasoning from basic
principles to determine whether the medicine-pharmaceutical
relationship, as it stands now, is an ethical one or not. That Dr.
Brody manages to deliver a hundred-odd pages of determinedly
objective analysis before he, too, lets the righteous indignation
roll should not really be called a failure of methodology: even as
he carefully lays out the facts in this impressively comprehensive
book, those facts begin to speak damningly for themselves . . . for
a detailed overview of this very jagged terrain, if not for a map
of the pathway out, a better general guide than this one is hard to
imagine. * The New York Times *
Physicians, policy makers, and the public should thank Dr. Brody
for this major contribution to our understanding of the medical
profession and the corrupting influence on the profession of its
complex relationship with the pharmaceutical industry. -- Philip R.
Lee, MD, Stanford University, and author of Pills, Profits, and
Politics
The single best, most balanced, most comprehensive guide to the
current difficulties with the pharmaceutical industry that I have
ever read. -- Carl Elliott, University of Minnesota
Dr. Howard Brody has written a powerful book that is relevant to
all out practices and questions the relationship between medicine
and the pharmaceutical industry. * The Journal Of Nuclear Medicine,
December 1, 2008 *
In this extraordinary book, Dr. Howard Brody, a medical ethicist,
lays out in great detail what he judges to be Big Pharma's misdeeds
and the seduction of U.S. docs. His targets are the influence of
company drug reps, the suppression of negative research data, the
abuse of patents, phony advertising and weak oversight by the FDA.
* Chicago Tribune *
Thoroughly documented, logically structured, and well written,
[Brody's] book offers a good starting point for discussing ethical
issues that impact us all. Recommended for all medical and public
libraries. * Library Journal *
I highly acclaim and recommend this book to all physicians, medical
students, and those in policy-making positions regarding our broken
health-care system...It ought to be required reading for the
medical profession as a whole and a call to action to help us
regain the public's trust in our integrity, altruism, and
professional ethics. * Explore: The Journal of Science and Healing
*
It seems that no stone is left unturned in this 367-page book,
which can feel at times overwhelming but is without a doubt,
thorough. * Health Affairs, September 2008 *
This book is useful for any medical student or resident who, like
me, finds the practice of distributing free pens and lunches a nice
perk but an ineffective marketing strategy. Hooked is surely
worthwhile for the academic physician-investigator who struggles to
win grants, or for the rural practitioner. * Anesthesia and
Analgesia, September 2008 *
The densely written book captures one's attention and reads like a
nonfiction thriller....I highly recommend this book to anyone who
wants to gain a thorough understanding of the relationship between
the pharmaceutical industry and the medical profession. This
knowledge provides a platform for the development of rational
solutions, which are sorely needed. * JAMA: The Journal of the
American Medical Association, (Jama) *
Hooked is a detailed analysis of the relationship between the
medical profession and the pharmaceutical industry primarily in the
United States. Hooked is well researched and well written. Brody's
style is fluent, helping make his arguments persuasive. -- Thomas
Harter, 2009 * Journal of Value Inquiry *
We still have too many doctors and patients who may be aware of
some of the deviances of the pharmaceutical industry, however,
consider these to be exceptional and of marginal importance. In
fact, if someone reads Brody's book, they will learn that fraud,
malpractice, and lying is an inbuilt phenomenon in the system of
clinical research, drug regulation, scientific publication, medical
training and drug advertisements. What Brody adds to our present
knowledge is a systematic collection of recommendations for
changing the present malfunctioning status quo. It is good to read
Brody's book, and it is good to have his reflections in our minds.
-- Imre Szebik * Metapsychology Online, July 7, 2009 *
An extremely timely book, recommended. * Pediatric Endocrinology
Reviews, (Per) *
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