Table of Contents

1 Preface.- 2 Epidemiology – US, European, and global perspectives; unstable angina, NSTEMI, STEMI.- 3 Diagnosis – symptoms, biomarkers, ECG.- 4 Risk stratification – TIMI risk score, GRACE risk score, CRUSADE/PURSUIT risk score.- 5 Medical therapy – antithrombotics, statins, etc.- 6 Percutaneous therapy – culprit vessel versus mulitvessel; BMS vs DES.- 7 Surgical therapy.- 8 Prognosis. - 9 Controversies – optimal antithrombotic strategy, fibrinolysis versus primary PCI for STEMI, preferred mode of revascularization (bare metal stents versus drug eluting stents versus CABG). - 10 Future approaches – CT angio and other evolving imaging modalities, biomarkers, proteomics, genomics, angiogenesis, myogenesis. Appendix A – Practice Guidelines – ACC/AHA and ESC.- Appendix B – Synopsis of Key Trials.